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FLUMIST (Influenza, Vaccine Live, Intranasal), the nation’s only nasal spray flu vaccine, now available for home delivery - BioSpace

Ravi Jhaveri, MD, Division Head, ... and better aligned with the realities and current preferences of people’s lives.”7 · Michele Slafkosky, Executive Director, Families Fighting Flu, said: “Seasonal influenza can have a serious, even life-altering, impact on individuals ... Ravi Jhaveri, MD, Division Head, Infectious Disease; Virginia H. Rogers Professor in Infectious Diseases, Professor of Pediatrics (Infectious Diseases), Northwestern University School of Medicine, Chicago, US, said: “As influenza vaccination rates decline, especially among younger populations, this first-of-its-kind, at-home, needle-free option offers a critical opportunity to help make protection more accessible, convenient, and better aligned with the realities and current preferences of people’s lives.”7 · Michele Slafkosky, Executive Director, Families Fighting Flu, said: “Seasonal influenza can have a serious, even life-altering, impact on individuals and families, especially for those most vulnerable.Before getting FLUMIST, tell your healthcare provider about all your medical conditions, including if you: are currently wheezing; have a history of wheezing and are under 5 years of age; have asthma; have had Guillain-Barré syndrome (severe muscle weakness); have a weakened immune system or live with someone who has a severely weakened immune system; have problems with your heart, kidneys, or lungs; have diabetes; are pregnant or nursing; or are taking antiviral drugs for the treatment of influenzaFLUMIST is a live attenuated influenza vaccine (LAIV), which is administered as a nasal spray for the prevention of influenza.9 FLUMIST is an Advisory Committee on Immunization Practices (ACIP) and American Academy of Pediatrics (AAP)-recommended influenza vaccine option.WILMINGTON, Del.--(BUSINESS WIRE)--AstraZeneca today launches FluMist Home, the first-of-its-kind, at-home delivery service for FLUMIST® (Influenza Vaccine Live, Intranasal).

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Influenza virus vaccine, live (nasal route) - Side effects & dosage - Mayo Clinic

The nasal mist vaccine (FluMist® or FluMist® Quadrivalent) contains a live virus. Avoid contact with people who are sick or at increased risk of getting the infection after you or your child receive this vaccine. This vaccine should not be given to children and teenagers (2 to 17 years of age) who are also using aspirin or any medicine that contains aspirin (eg, Aggrenox®, Ecotrin®, Excedrin®, Soma® Compound, and many cold medicines). Also, children and teenagers should not be given aspirin for 4 weeks after getting FluMist® or FluMist® Quadrivalent unless your doctor tells you otherwise.Children younger than 2 years of age are usually not given the flu vaccine nasal spray.Young children who need the flu vaccine are usually given the flu vaccine injection (a shot).

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Prevention and Control of Seasonal Influenza...

Information for the 2025–26 influenza season includes the updated vaccine composition, approval of FluMist (nasal spray live attenuated influenza vaccine) for self-administration or caregiver administration, expansion of the approved age threshold for Flublok (recombinant influenza vaccine) ... Information for the 2025–26 influenza season includes the updated vaccine composition, approval of FluMist (nasal spray live attenuated influenza vaccine) for self-administration or caregiver administration, expansion of the approved age threshold for Flublok (recombinant influenza vaccine) from ≥18 years to ≥9 years, and a recommendation that only single-dose seasonal influenza vaccines not containing thimerosal as a preservative be used.Multiple formulations of the trivalent inactivated influenza vaccines (IIV3s), trivalent recombinant influenza vaccine (RIV3), and trivalent live attenuated influenza vaccine (LAIV3) are expected to be available for the 2025–26 influenza season. Updates for the 2025–26 season include 1) antigenic composition of 2025–26 U.S. seasonal influenza vaccines, 2) Food and Drug Administration (FDA) approval of FluMist (LAIV3) for self-administration or caregiver administration, 3) FDA approval of a change in age indication for Flublok (RIV3) from ≥18 years to ≥9 years, and 4) a new ACIP recommendation that children aged ≤18 years, pregnant women, and all adults receive seasonal influenza vaccines only in single-dose formulations that are free of thimerosal as a preservative.FluMist (LAIV3). In September 2024, FDA approved the nasal spray live attenuated influenza vaccine FluMist (LAIV3) for self-administration (for recipients aged 18 through 49 years) or administration by a caregiver aged ≥18 years (for children and adolescents aged 2 through 17 years) (11).Abbreviations: ACIP = Advisory Committee on Immunization Practices; aIIV3 = adjuvanted inactivated influenza vaccine, trivalent; ccIIV3 = cell culture–based inactivated influenza vaccine, trivalent; FDA = Food and Drug Administration; FFU = fluorescent focus units; HA = hemagglutinin; HD-IIV3 = high-dose inactivated influenza vaccine, trivalent; Hg = mercury; IIV3 = inactivated influenza vaccine, trivalent; IM = intramuscular; LAIV3 = live attenuated influenza vaccine, trivalent; MDV = multidose vial; PFS = prefilled syringe; RIV3 = recombinant influenza vaccine, trivalent.

Search Results | HealthLink BC

… Series What is the live attenuated influenza vaccine? The live attenuated influenza vaccine (LAIV) is made from weakened influenza … viruses and is given as a nasal spray. … 12b Influenza (Flu) Series What is influenza? … nose Anti-influenza drugs or antivirals are available by prescription, but these must be … start of your symptoms to work best.… Series What is the live attenuated influenza vaccine? The live attenuated influenza vaccine (LAIV) is made from weakened influenza … viruses and is given as a nasal spray.

Live attenuated influenza vaccine - Wikipedia

The live attenuated vaccine is based on a flu strain that does not cause disease, that replicates well at relatively cold temperatures (about 25 °C (77 °F), for incubation purposes), and replicates poorly at body temperature (which minimizes risk to humans). It is an attenuated live vaccine, unlike other influenza vaccines, which are inactivated vaccines. LAIV is administered intranasally,‍ while inactivated vaccines are administered by intramuscular injection. LAIV is sold under the brand names FluMist and FluMist Quadrivalent in the United States; and the brand name Fluenz Tetra in the European Union.‍‍ FluMist was first introduced in 2003 by MedImmune.‍‍In the United States, FluMist is approved for self- or caregiver-administration.‍‍ It is the first influenza vaccine that does not need to be administered by a health care provider.‍ · The live attenuated influenza vaccine is used to provide protection against the flu, caused by infection with influenza viruses.‍‍‍The live attenuated vaccine is based on a flu strain that does not cause disease, that replicates well at relatively cold temperatures (about 25 °C (77 °F), for incubation purposes), and replicates poorly at body temperature (which minimizes risk to humans).The higher price hampered sales of the original frozen version of FluMist; FluMist was initially priced higher than injectable vaccines, and sold only 500,000 of the four million doses produced its first year on the market, despite a comparative shortage of flu vaccine in fall 2004.‍ The price was sharply lowered the next year, and MedImmune reported distributing 1.6 million doses in 2005.‍ Because of the price drop, despite selling almost three times as many doses in 2005, the company reported $21 million in revenue from FluMist sales,‍ compared to $48 million the previous year.‍‍ ·It was the first and, as of 2007, the only live attenuated vaccine for influenza available outside of Europe.‍ In September 2009, a live attenuated influenza vaccine for the novel H1N1 influenza virus was approved.‍ In 2011, the vaccine was approved by the European Medicines Agency (EMA) for use in the European Union under the brand name Fluenz.‍‍

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Flu Myths: Dispelling the Myths Associated With Live Attenuated Influenza Vaccine - Mayo Clinic Proceedings

Despite the colloquial use of the term flu for wintertime infections, influenza is a serious infection causing substantial morbidity and mortality worldwide and resulting in approximately 250,000 to 500,000 deaths per year.1 Influenza epidemics and pandemics have had disastrous effects on a ... Despite the colloquial use of the term flu for wintertime infections, influenza is a serious infection causing substantial morbidity and mortality worldwide and resulting in approximately 250,000 to 500,000 deaths per year.1 Influenza epidemics and pandemics have had disastrous effects on a global scale. For example, the influenza pandemic of 1918 claimed many more lives than World War I, which was being fought at the time.2 Even in years of relatively mild epidemics, almost 3 times as many Americans die of influenza as of human immunodeficiency virus (HIV) infection and AIDS.3,4 Safe and effective vaccines have been developed that have been useful in preventing this disease.Safety of a trivalent live attenuated intranasal influenza vaccine, FluMist, administered in addition to parenteral trivalent inactivated influenza vaccine to seniors with chronic medical conditionsLive attenuated influenza vaccine (LAIV), commercially available since 2003, has not gained widespread acceptance among prescribers. This underuse can be traced to several misperceptions and fears regarding LAIV. This review examines both the facts (safety, immunogenicity, and effectiveness) and the most pervasive myths about LAIV.Many of the TIV-related limitations have been addressed by the creation of a trivalent, intranasal, cold-adapted LAIV (FluMist; MedImmune, Gaithersburg, MD).

Does the Flu Shot Contain Live Virus? Here's What to Know and Why It's Safe

In particular, live, attenuated vaccines contain a live but weakened version of a virus or bacteria, while inactivated vaccines contain an inactivated version of a virus or bacteria. "Many years ago, when we first started getting flu shots, they were live attenuated virus vaccines," said Dr. In particular, live, attenuated vaccines contain a live but weakened version of a virus or bacteria, while inactivated vaccines contain an inactivated version of a virus or bacteria. "Many years ago, when we first started getting flu shots, they were live attenuated virus vaccines," said Dr.Consequently, later flu vaccines contained inactivated viruses, which eliminated the chance of getting sick after a flu vaccination. However, though most flu vaccines contain inactivated viruses, there is one flu vaccine that does include a live, attenuated virus.Centers for Disease Control and Prevention. Live, attenuated influenza vaccine VIS. Centers for Disease Control and Prevention. How influenza (flu) vaccines are made.U.S. Food and Drug Administration. FDA’s critical role in ensuring safe and effective flu vaccines. Centers for Disease Control and Prevention. Live, attenuated influenza vaccine VIS.

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Are Flu Vaccines Live or Attenuated? - Families Fighting Flu

Most flu vaccines are not live or attenuated. Live means that the virus is not dead, and attenuated means that the virus is weakened but still alive. The live attenuated flu vaccine contains a version of the flu virus that is “alive” but weakened so that it cannot reproduce and… The live attenuated flu vaccine contains a version of the flu virus that is “alive” but weakened so that it cannot reproduce and make you sick. Rather, it protects against future flu infections by creating antibodies.While the live attenuated flu vaccine is a great option for those who qualify because there is no needle needed, the fact that the virus is live but weakened means some people shouldn’t receive it. Live viruses pose a risk to people who are pregnant and/or immunocompromised.Instead, they should get the injected flu vaccine because it contains inactivated (dead) flu virus. ... People who care for severely immunocompromised persons who require a protected environment (or otherwise avoid contact with those persons for 7 days after getting the nasal spray vaccine) ... We work hard to make sure that at least 80% of your donation dollars go directly to program-related expenses. Your tax-deductible donations help us continue our education and advocacy programs in an effort to save lives.The only live attenuated flu vaccine is the nasal spray vaccine, which is injected up the nose and doesn’t require a needle.

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Influenza, live intranasal Vaccine Information Statement

Download and print official up-to-date influenza (live intranasal) VISs in English and Spanish, plus other languages. PDF format. 65+ Flu Defense · Protect vulnerable, older adult patients from influenza. Give2MenACWY.org · Improve protection from meningococcal serogroups ACWY.Recognizing ExcellenceOur honor rolls for institutions with vaccination policies that protect lives, plus our Becky Payne Award recipients

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AstraZeneca launches at-home FluMist nasal spray delivery - ABC News

FluMist is a live attenuated vaccine that comes in the form of a nasal spray as a needle-free option for those who qualify. Starting Friday, Americans can order the nasal spray flu vaccine online and have it shipped directly to their home.The FDA says FluMist is not recommended for children under 2 years of age due to an increased risk of wheezing and breathing problems after vaccination and is not recommended for those over 49 years old because it has not been shown to be effective in this age group.On the market since 2003, FluMist was previously only available at pharmacies or doctors' offices.AstraZeneca is making flu protection more convenient with the launch of an at-home delivery option for FluMist, its nasal spray flu vaccine, the company announced Friday.

Types of seasonal influenza vaccine

Two types of influenza vaccine are widely available: inactivated influenza vaccines (IIV) and live attenuated influenza vaccines (LAIV). Traditionally, influenza vaccines (both IIV and LAIV) have been produced to protect against 3 different seasonal influenza viruses (also called trivalent ... Two types of influenza vaccine are widely available: inactivated influenza vaccines (IIV) and live attenuated influenza vaccines (LAIV). Traditionally, influenza vaccines (both IIV and LAIV) have been produced to protect against 3 different seasonal influenza viruses (also called trivalent vaccines).

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New At-Home Vaccine Helps Reduce Flu Risk for Most

However, since FluMist, which is manufactured by AstraZeneca, is a live attenuated form of the vaccine, that comes with certain limitations, including for those who may be immunocompromised. FluMist is what’s known as a live attenuated influenza vaccine (LAIV), meaning the vax contains a weakened form of the virus.Immune Deficiency and Live Vaccine: American Academy of Allergy, Asthma, & Immunology. “Flu Vaccine Guidance for Patients with Immune Deficiency.” https://www.aaaai.org/tools-for-the-public/conditions-library/immuno-deficiency/flu-vaccine-guidanceA DIY mist-based flu vaccine offers convenience and no needles, but people with certain chronic health conditions should proceed with caution.A nasal spray approved for home use can help prevent flu infection, but those with certain chronic health conditions may not benefit.

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No bird flu death in 72 hours, says Delhi zoo | Latest News Delhi

Stay informed on the latest happenings in World News along with Delhi Election 2025 and Delhi Election Result 2025 Live, New Delhi Election Result Live, Kalkaji Election Result Live at Hindustan Times. News / Cities / Delhi / No bird flu death in 72 hours, says Delhi zoo Delhi zoo reports no new avian flu deaths in 72 hours, but remains closed since August 30 after bird deaths; future reopening depends on test results. | Latest News DelhiThe zoo was shut on August 30, after lab tests confirmed bird deaths due to avian influenza (bird flu).Catch every big hit, every wicket with Crickit, a one stop destination for Live Scores, Match Stats, Infographics & much more. Explore now! Stay updated with all top Cities including, Bengaluru, Delhi, Mumbai and more across India.

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RFK's proposal to let bird flu spread through poultry could set us up for a pandemic, experts warn | Live Science

Viruses, Infections & Disease Doctors could combat antibiotic resistance — and save lives — by tracking superbug evolution in real time, study hints · Viruses, Infections & Disease Scientist's cat helps discover a rare virus — yet again · Medicine & Drugs Scientists gave mice flu vaccines ... Viruses, Infections & Disease Doctors could combat antibiotic resistance — and save lives — by tracking superbug evolution in real time, study hints · Viruses, Infections & Disease Scientist's cat helps discover a rare virus — yet again · Medicine & Drugs Scientists gave mice flu vaccines by flossing their tiny teeth — and it workedErin Sorrell, a virologist at the Johns Hopkins Center for Health Security, told Live Science. "Worse case scenario, the virus adapts and expands its host range to become transmissible in humans … Now we have a pandemic." ... influenza (HPAI), a type of bird flu that can cause severe disease and death in poultry and other birds.—Teen sickened with Canada's first human case of bird flu is in critical condition — and the source remains a mystery · Other experts agree with the team's suggestions, although they highlighted areas that need further discussion. Dr. Rocio Crespo, a poultry veterinarian at the North Carolina State University College of Veterinary Medicine, told Live Science that further details on potential vaccine strategies and biosecurity at farms should be explored.facing billions of dollars in federal funding cuts, and Crespo says that providing economic support to farmers facing outbreaks — alongside making investments to understand bird flu evolution, preventive measures and control methods — could become increasingly difficult. "The current policies on poultry farms are effective at preventing spread to other farms," Crespo told Live Science.

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Now You Can Get Your Flu Vaccine at Home | WIRED

It was the most severe flu season ... swine flu pandemic. AstraZeneca’s September 2024 approval was based on a study with vaccine recipients and caregivers to evaluate whether the instructions for use were appropriately designed so that they could safely and effectively use the vaccine. The vaccine contains a weakened form of the live influenza ... It was the most severe flu season since the 2009 H1N1 swine flu pandemic. AstraZeneca’s September 2024 approval was based on a study with vaccine recipients and caregivers to evaluate whether the instructions for use were appropriately designed so that they could safely and effectively use the vaccine. The vaccine contains a weakened form of the live influenza virus and protects against four types of flu strains.“We recognized that people's daily lives are busier than ever, and we knew we needed to meet people where they are facing the realities of real life,” said Tonya Villafana, vice president of medical and scientific affairs at AstraZeneca, at a press conference on Thursday. “FluMist Home is designed to remove traditional obstacles to vaccination, things like scheduling clinic visits, waiting in line, and the fear of needles.”The nasal spray vaccine FluMist can now be ordered online and shipped to your door.Starting today, AstraZeneca’s FluMist is available through an online pharmacy in 34 states. FluMist is not a new vaccine. It was originally approved by the Food and Drug Administration in 2003 and previously could only be administered by a health care professional.

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Needle-phobic? FluMist nasal spray vaccine available in lieu of flu shot

The FluMist Home vaccine contains a weakened form of a live virus to stimulate the immune system. Doctors are hoping that the first nasal flu vaccine available for use at home can improve vaccination rates among people who are afraid of needles.The majority of children and up to 30% of young adults have a fear of needles, research shows.However, after the 2009 swine flu pandemic introduced the new H1N1 strain, several studies found the nasal spray was less effective than other flu vaccines. This prompted the Centers for Disease Control and Prevention to recommend against using the nasal spray in 2016.More children died from the flu this past season than any year outside of the swine flu pandemic in 2009.

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You Can Now Vaccinate Yourself Against the Flu | TIME

While the flu shot can cause redness ... runny nose, congestion, sore throat, cough, fever, and muscle aches. That’s because FluMist is made from weakened forms of the live virus.... While the flu shot can cause redness and soreness at the injection site, as well as fever, muscle aches, headache and fatigue, FluMist can cause flu-like symptoms, including runny nose, congestion, sore throat, cough, fever, and muscle aches. That’s because FluMist is made from weakened forms of the live virus.You no longer need a doctor to administer FluMist, the nasal flu vaccine.When you’re ready to get your flu vaccine this year, you have a convenient new option: you can skip the doctors’ office or pharmacy and inoculate yourself. FluMist, a vaccine sprayed up the nose to protect people from serious influenza symptoms, is now available for anyone in the U.S.FluMist, made by AstraZeneca, has been available since 2003. But even though it’s relatively easy to administer, it still required a health care professional to give to people. in Sept. 2024, however, the U.S.

FluMist® (Influenza Vaccine Live, Intranasal) | Nasal Spray ...

Discover FluMist® (Influenza Vaccine Live, Intranasal) – a needle-free nasal spray flu vaccine that helps protect against seasonal influenza. Learn how it works and who it's for. Before getting FLUMIST, tell your healthcare provider about all your medical conditions, including if you: are currently wheezing; have a history of wheezing and are under 5 years of age; have asthma; have had Guillain-Barré syndrome (severe muscle weakness); have a weakened immune system or live with someone who has a severely weakened immune system; have problems with your heart, kidneys, or lungs; have diabetes; are pregnant or nursing; or are taking antiviral drugs for the treatment of influenzaYou should not get FLUMIST if you have a severe allergy to its components, eggs or other flu vaccines; or are 2 through 17 years old and take aspirin or medicines containing aspirin - children or adolescents should not be given aspirin for 4 weeks after getting FLUMIST unless your healthcare provider tells you otherwiseYou are about to enter the FluMist site for healthcare professionals. The information in this site is for US healthcare professionals only.You are now leaving the FluMist website and headed to our third-party online pharmacy partner, who will help you from here.

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Live, Attenuated Influenza Vaccine VIS | Vaccines & Immunizations | CDC

Children 6 months through 8 years of age may need 2 doses during a single flu season. Everyone else needs only 1 dose each flu season. Live, attenuated influenza vaccine (called "LAIV") is a nasal spray vaccine that may be given to men and non-pregnant women 2 through 49 years of age. Children 6 months through 8 years of age may need 2 doses during a single flu season. Everyone else needs only 1 dose each flu season. Live, attenuated influenza vaccine (called "LAIV") is a nasal spray vaccine that may be given to men and non-pregnant women 2 through 49 years of age.Influenza vaccine does not cause flu. Influenza vaccine may be given at the same time as other vaccines. Tell your vaccination provider if the person getting the vaccine: Is younger than 2 years or older than 49 years of age · Is pregnant. Live, attenuated influenza vaccine is not recommended for pregnant womenHas a cerebrospinal fluid leak (a leak of the fluid that surrounds the brain to the nose, throat, ear, or some other location in the head) Has had Guillain-Barré Syndrome within 6 weeks after a previous dose of influenza vaccine · In some cases, your health care provider may decide to postpone influenza vaccination until a future visit. For some patients, a different type of influenza vaccine (inactivated or recombinant influenza vaccine) might be more appropriate than live, attenuated influenza vaccine.Has other underlying medical conditions that can put people at higher risk of serious flu complications (such as lung disease, heart disease, kidney disease like diabetes, kidney or liver disorders, neurologic or neuromuscular or metabolic disorders)

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